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Sunday, March 20, 2011 |
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| 4:00pm |
Hotel Check-in
On your own for dinner tonight |
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| 6:00pm |
Registration |
Location: Foyer of Cypress Ballroom |
| 6:30pm |
Welcome Reception
Beer, wine and light snacks |
Location: Foyer of Cypress Ballroom |
| 7:30pm |
Opening comments
Tom Poulos
University of California, Irvine
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Location: Cypress Ballroom |
| Keynote Speaker |
| 7:45pm |
Harry F. Noller
University of California Santa Cruz
Ribosome Structure and Dynamics |
Location: Cypress Ballroom
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| 9:00pm |
Social
Beer, wine and snack |
Location: Foyer of Cypress Ballroom |
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| Monday, March 21, 2011 |
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| 8:00am |
Continental Breakfast |
Location: Lower Terrace (weather permitting) |
| Session 1: METHODOLOGY
Discussion Leader- Alex McPherson, University of California, Irvine
Location: Cypress Ballroom
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| 8:50am |
Rick Bott, Genencor, "The role of temperature in visualizing flexible domains" |
| 9:10am |
Matthew Warkentin, LBL, "New results using temperature-dependent protein crystallography" |
| 9:30am |
James S. Fraser, UCSF, "Crystal freezing biases protein packing and obscures functional motions' |
| 9:50am |
James Holton, LBL, "The noise level of electron density maps" |
| 10:10am |
P. Therese Lang, UC Berkeley, "Revealing structural ensembles hidden in electron density"
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| 10:30am |
Coffee Break |
Location: Foyer of Cypress Ballroom |
Session 2: CRYSTAL COMPLEXES
Discussion Leader- Celia Goulding, University of California, Irvine
Location: Cypress Ballroom
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| 10:50am |
Zachary A. Bornholdt , Scripps, "Ebola virus: Some assembly required" |
| 11:10am |
Minglei Zhao, UCLA, "Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation" |
| 11:30am |
Heidi L. Schubert, Univ. Utah, "The nuclear Arp heterodimer bound to an HSA-domain" |
| 11:50am |
Ron Diskin, CalTech, "Crystal structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody" |
| 12:10pm |
Ryan VanderLinden, Univ. Utah, "The X-ray Crystal Structure of Rpn13:Uch37: Ubiquitin Complex and Implications for Uch37 Activation and Function" |
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| Monday March 21, 2011 |
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| 12:30pm |
Lunch |
Location: Upper Plaza (weather permitting) |
| 1:00pm |
Free time |
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| 6:00pm |
Dinner |
Location: Dolphins Room (located right off the Upper Plaza) |
Session 3: MEMBRANE PROTEINS
Discussion Leader: Hartmut "Hudel" Luecke, University California, Irvine
Location: Cypress Ballroom
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| 7:30pm |
Eric Johnson, CalTech, "Relating conformational changes the ATPase active state in the E. Coli high-affinity methionine ABC transporter MetNI" |
| 7:50pm |
Theresa Tiefenbrunn, Scripps, "The 1.8 Å Resolution Structure of Cytochrome ba3 Oxidase Obtained From the Lipidic Cubic Phase" |
| 8:10pm |
Troy Walton, CalTech, "Exploring the structural role of the MscL cytoplasmic bundle" |
| 8:30pm |
James Holton, LBL, “X-ray lasers: no longer science fiction”
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| 8:50pm |
Social and Poster Session |
Location: Monterey Bay Room |
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| Tuesday, March 22, 2011 |
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| 8:00am |
Continental Breakfast |
Location: Lower Terrace (weather permitting) |
Session 4: METHODOLOGY
Discussion Leader: Howard Einspahr, IUCr Journals
Location: Cypress Ballroom
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| 8:50am |
James Holton, LBL, "What is "good enough"? Predicting the success or failure of structure solution from first principles" |
| 9:10am |
Puneet Souda, UCLA, "High Resolution Mass Spectrometry to Profile Integral Membrane Proteins And Their Post Translational Modifications" |
9:30am |
Tzanko Doukov, SSRL, "Crystallographic and Single Crystal Spectral Analysis of the Peroxidase Ferryl Intermediate" |
9:50am |
Allen M. Orville, BNL, "Removing the Mystery from Mystery Density in X-ray Crystallography with Single-Crystal Spectroscopy" |
10:10am |
Rachna Ujwal, UCLA, "High-throughput crystallization of membrane proteins using lipidic bicelle method"
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| 10:30am |
Coffee Break |
Location: Foyer of Cypress Ballroom |
Session 5: MECHANISMS
Discussion Leader: Heidi Schubert, University of Utah
Location: Cypress Ballroom
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| 10:50am |
Eric Montemayor, Univ. Texas Health Sci. Ctr. San Antonio, "Structures of the RNA Lariat Debranching Enzyme Dbr" |
| 11:10am |
John C. Williams, City of Hope, "The role of valency on the regulation of protein function: Structural, biochemical and in vivo studies of the dynein regulatory subunits" |
11:30am |
Rick Cooley, Oregon State, "Symerythrin: an unorthodox story of protein evolution from a simple peptide to the most powerful oxidizing enzymes in biology" |
11:50am |
Elizabeth J. Goldsmith, Uni. Texas. Southwest. Med. Ctr. Dallas, "The third conformer of p38α observed in solution and in phosphorylated p38α" |
| 12:10am |
Camden M. Driggers, Oregon State, "Structural Studies Toward Understanding the Mechanism of Mammalian Cysteine Dioxygenase"
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| 12:30pm |
Lunch |
Location: Upper Plaza (weather permitting) |
| 1:00pm |
Free time |
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| 6:30pm |
Dinner |
Location: Dolphins Room (located right off the Upper Plaza) |
Session 6: METHODOLOGY 3
Discussion Leader: Allen Orville, Brookhaven National Laboratory
Location: Cypress Ballroom
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| 7:30pm |
Jeffrey J. Headd, LBL, "Knowledge-based restraints in phenix.refine for improved macromolecular refinement at low resolution" |
7:50pm |
Dale Tronrud, Oregon State, "Using a Conformationally-Dependent Stereochemical Library Improves Crystallographic Refinement of Proteins" |
8:10pm |
Alex McPherson, UCI, "1.45 Å Resolution Refinement of STMV" |
| 8:30pm |
Lida K. Gifford, LBL, "PSI SBKB Technology Portal: A Web Resource for Structural Biologists"
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| 9:00pm |
Social and Posters |
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Wednesday, March 23, 2011 |
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Session 7: CRYSTALLOGRAPHY AND MEDICINE
Discussion Leader: Sheryl Tsai, University of California, Irvine
Location: Cypress Ballroom
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8:50am |
Hay Dvir, La Jolla Institute for Allergy & Immunology, "Structure of the LDL receptor tail in complex with ARH: Implications to Hypercholesterolemia" |
9:10am |
Argentina Becker, Univ. Texas Health Sci. Ctr. San Antonio, "The Structure of CARDS Toxin from Mycoplasma pneumonia" |
9:30am |
Enrico Girardi, La Jolla Institute for Allergy & Immunology, "Recognition of microbial antigens by the invariant NKT TCR
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9:50am |
Debasish Chattopadhyay, Univ. Alabama, Birmingham, "Trypanosoma cruzi Dihydrofolate Reductase Thymidylate Synthase: a potential target for drugs against Chagas' disease" |
10:10am |
Ahmad Galaleldeen, Univ. Texas Health Sci. Ctr. San Antonio, "Structure of the Chlamydial Effector Protein Pgp3"
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| 10:30am |
Coffee Break |
Location: Foyer of Cypress Ballroom |
Session 8: NEW STRUCTURES AND MECHANISM
Discussion Leader: John Williams, Brookhaven National Laboratory
Location: Cypress Ballroom
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10:50am |
Eva Rose M. Balog, UCSC, "The structure of a monomeric mutant Cks protein reveals multiple roles for a conserved hinge-region proline" |
11:10am |
Seth M. McDonald, UCSC, "Structure and Biochemistry of the Yeast Transcription Factors Spt6 and Spn1/Iws1" |
11:30am |
Victoria S. Jasion, UCI, "The Crystal Structure of Leishmania major Peroxidase and Characterization of the Compound I Tryptophan Radical"
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11:50pm |
Sheryl Tsai, UCI, "Structural Basis of Polyketide Cyclization" |
12:10pm |
Arthur Laganowsky, UCLA, "Revealing the structural mechanisms of alpha crystallins in eye lens transparency"
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12:30pm |
Poster/oral presentation awards, next WCPCW organizer, farewell |
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